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Tissue typing clinical scientists are responsible for genetically matching patients with possible organ and stem cell (including bone marrow) donors.

Clinical tissue typers analyse specimens of blood, tissues and so on via computer-aided and detailed scientific testing procedures. Most of their work is laboratory based. Key tasks include:

• using molecular techniques to routinely tissue type patients and donors

• assigning donors and patients according to tissue type

• undertaking donor/patient screening to identify particular antibodies

• isolating, measuring and cataloguing DNA samples

• isolating and preserving lymphocytes (a type of white blood cell important to the immune system)

• undertaking bone marrow transplant cellular assessments

• offering advice to clinicians about best donor/patient matches

Other responsibilities include:

• laboratory management

• writing reports

• maintaining computerised records

• participating in research and development activities

Qualifications and training required

A degree in a relevant subject such as biochemistry, chemistry, immunology or genetics is required for entry. A postgraduate qualification, research work, hospital laboratory placements and/or experience gained using similar scientific and analytical techniques can be beneficial.

Key skills for tissue typing clinical scientists

• Ability to work quickly and accurately

• A logical and inquisitive mind

• Good experimental and research skills

• Communication skills

• Teamwork skills

Typical employers of tissue typing clinical scientists

• NHS Blood and Transplant

• Immunology department of NHS hospitals

• The Anthony Nolan Trust

• Teaching hospitals and universities